Institut de Neurociències (INc) - UAB Barcelona

13 research projects will be funded

13 research projects will be funded

The Spanish Research Agency published last Friday the provisional resolution for the R+D+i Projects 2020 call «Retos Investigación» and «Generación de Conocimiento». 13 projects by our researchers will be funded, receiving a total of 2 million euros. Congrats!

21/06/2021

Resolution



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The H2020 project QSPainRelief awarded by the European Commission

The H2020 project QSPainRelief awarded by the European Commission

The QSPainRelief project "Effective combinational treatment of chronic pain in individual patients by an innovative quantitative systems pharmacology pain relief approach", which includes the participation of Dr. Jesús Giraldo’s team (Institute for Neurosciences and Biostatistics Unit of the School of Medicine), has been funded from the European Commission.

This  project will attempt to solve a crucial problem since about 20% of Europeans suffer from chronic pain and current therapies are not effective in many cases. Around 60% of patients do not reach enough relief from traditional painkillers, which in turn can lead to several adverse effects.

The QSPainRelief project addresses the problem of chronic pain by identifying new drug combinations that are expected to increase analgesic efficacy while reducing side effects. To do this, quantitative systems pharmacology and computational modeling will be used. The best combinations will be validated in animal models and clinical studies.

The QSPainRelief project will receive more than € 6 million in funding for 5 years through the H2020 program. The project is a collaboration between 9 research institutions from 6 different countries, including the UAB, starting January 1, 2020.

A new model of the worm C. elegans to progress in the study of a rare disease of the nervous system

A new model of the worm C. elegans to progress in the study of a rare disease of the nervous system

In a research co-directed by Dr Esther Dalfó, researcher at the Institute and professor at UVic-UCC, a model of chromosome X-linked adrenoleukodystrophy (x-ALD) has been indentified in the earthworm C. elegans.

The model will permit to accelerate and reduce the price of the research, which is studying the mechanisms and the possible pharmacological targets for the neuronal alterations of this disease.

The earliest results of studies with this organism point to glial cells as a man responsible for the neurological damage caused by the disease.

The work was done at the IDIBELL Neurometabolic Diseases group, with international collaborations, and has been published in the Free Radical Biology and Medicine journal.

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